References
References
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Mouse Type SID Disease Model Journal Exp Mol Med. 2025 Mar;57(3):616-627. doi: 10.1038/s12276-025-01416-1. Author Dong-Hoon Chae, Hyun Sung Park, Kyoung-Myeon Kim, Aaron Yu, Jae Han Park, Mi-Kyung Oh, Soon Won Choi, Jaechul Ryu, Cynthia E Dunbar, Hee Min Yoo, Kyung-Rok Yu Title of Publication SARS-CoV-2 pseudovirus dysregulates hematopoiesis and induces inflammaging of hematopoietic stem and progenitor cells. -
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Mouse Type SID Disease Model Journal J Exp Clin Cancer Res. 2025 Apr 7;44(1):114. doi: 10.1186/s13046-025-03372-0. Author Su Jung Park, Claudia Cerella , Jin Mo Kang, Jinyoung Byun, David Kum, Barbora Orlikova-Boyer, Anne Lorant, Michael Schnekenburger, Ali Al-Mourabit, Christo Christov, Juyong Lee, Byung Woo Han, Marc Diederich Title of Publication Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming. -
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Mouse Type huHSC SID Disease Model Journal J Immunother Cancer 2025 Apr 5;13(4):e011422. doi: 10.1136/jitc-2024-011422. Author Ik-Hwan Han, Ilseob Choi, Hongseo Choi, Soyoung Kim, Chanmi Jeong, Juwon Yang, Yingying Cao, Jeongyoon Choi, Heekyung Lee, Jin Sun Shin, Hye Duck Yeom, Eun-Ji Lee, Nari Cha, Hyemin Go, Se Eun Lim, Songah Chae, Won-Jun Lee, Minjin Kwon, Hongsung Kim, Hyojung Choi, Sehyun Pak, Namgyeong Park, Eunbin Ko, Deok-Sang Hwang, Junho H Lee, Hwan-Suck Chung, Seong Ho Kang, Hyunsu Bae Title of Publication Conformation-sensitive targeting of CD18 depletes M2-like tumor-associated macrophages resulting in inhibition of solid tumor progression. -
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Mouse Type huPBMC SID Disease Model Journal Cancer Immunol Res. 2024 Apr 2;12(4):491-507. doi: 10.1158/2326-6066.CIR-23-0817. Author Dong-In Koh, Minki Lee, Yoon Sun Park, Jae-Sik Shin, Joseph Kim, Yea Seong Ryu, Jun Hyung Lee, Seunggeon Bae, Mi So Lee, Jun Ki Hong, Hong-Rae Jeong, Mingee Choi, Seung-Woo Hong, Dong Kwan Kim, Hyun-Kyung Lee, Bomi Kim, Yoo Sang Yoon, Dong-Hoon Jin Title of Publication The Immune Suppressor IGSF1 as a Potential Target for Cancer Immunotherapy. -
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Mouse Type SID Disease Model Journal Sci Rep 2024 Oct 9;14(1):23531. doi: 10.1038/s41598-024-75493-z. Author Hee Jung Kwon, Jang Woo Park, Hye Kyung Chung, Joohee Jung Title of Publication Comprehensive model for simultaneous monitoring of primary tumor to metastatic cancer utilizing Prkdc and Il2rg double knockout mice. -
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Mouse Type huHSC RID Disease Model Journal Front Immunol. 2024 Jul 26:15:1365946. doi: 10.3389/ fimmu.2024.1365946. Author Kang-Hyun Kim, Sang-Wook Lee, In-Jeoung Baek , Hye-Young Song, Seon-Ju Jo, Je-Won Ryu, Seung-Hee Ryu, Jin-Hee Seo, Jong-Choon Kim, Seung-Ho Heo. Title of Publication CD47;Rag2;IL-2rγ triple knock-out mice pre-conditioning with busulfan could be a novel platform for generating hematopoietic stem cells engrafted humanized mice. -
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Mouse Type SID Disease Model Journal Nat Commun. 2024 Feb 19;15(1):1487. doi: 10.1038/s41467-024-45647-8. Author Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong , Han-Woong Lee , Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek. Title of Publication PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development. -
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Mouse Type huHSC SID Disease Model Journal Sci Rep 2024 May 24;14(1):11894. doi: 10.1038/s41598-024-60501-z. Author Sung Wan Kang, Ji-Young Lee, Ok-Ju Kang, Yong-Man Kim, Eun Kyung Choi , Shin-Wha Lee Title of Publication Transcriptome profiling and characterization of peritoneal metastasis ovarian cancer xenografts in humanized mice. -
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Mouse Type huHSC SID Disease Model Journal International Immunopharmacology 121 (2023) 110451 Author Ji Hye Jeong, Sujin Park, Sangyeon Lee, Yeounhee Kim, In Kyong Shim, Seong-Yun Jeong, Eun Kyung Choi, Jinju Kim, Eunsung Jun Title of Publication Orthotopic model of pancreatic cancer using CD34+ humanized mice and generation of tumor organoids from humanized tumors. -
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Mouse Type huHSC SID Disease Model Journal Cell Death Differ. 2023 Dec;30(12):2491-2507. Author Joseph Kim , Dong-In Koh , Minki Lee , Yoon Sun Park, Seung-Woo Hong, Jae-Sik Shin , Mi So Lee, Min-Hwa Kim, Jun Hyung Lee, Joonyee Jeong, Seunggeon Bae, Jun Ki Hong, Hong-Rae Jeong, Yea Seong Ryu, Seung-Mi Kim, Mingee Choi, Hyojin Kim, Hyun Ryu, Sun-Chul Hur, Junho Park, Dae Young Hur, Dong-Hoon Jin Title of Publication Targeting isoforms of RON kinase (MST1R) drives antitumor efficacy. -
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Mouse Type SID Disease Model Metastatic pancreatic cancer Journal Gastroenterology 2023 Jul;165(1):133-148.e17. doi: 10.1053/j.gastro.2023.02.049. Author Hye-Been Yoo, Jin Woo Moon, Hwa-Ryeon Kim, Hee Seung Lee, Koji Miyabayashi, Chan Hee Park, Sabrina Ge, Amy Zhang, Yoo Keung Tae, Yujin Sub, Hyun-Woo Park, Heon Yung Gee, Faiyaz Notta, David A. Tuveson, Seungmin Bang, Mi-Young Kim, and Jae-Seok Roe Title of Publication A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer. -
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Mouse Type RID Disease Model Pancreatic cancer Journal Applied Microbiology and Biotechnology (2021) 105:8343–8358 Author Kihak Lee, Hyo Jae Oh, Min‑Su Kang, Sinae Kim, Sehee Ahn, Myung Ji Kim, Seon‑Won Kim, Suhwan Chang Title of Publication Metagenomic analysis of gut microbiome reveals a dynamic change in Alistipes onderdonkii in the preclinical model of pancreatic cancer, suppressing its proliferation. -
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Mouse Type huHSC SID Disease Model Journal Cells 2021, 10, 2734. https://doi.org/10.3390/cells10102734 Author Jae Yun Jung, Hyun Jin Ryu, Seung-Hwan Lee, Dong-Young Kim, Myung Ji Kim, Eun Ji Lee ,Yeon-Mi Ryu, Sang-Yeob Kim, Kyu-Pyo Kim, Eun Young Choi, Hyung Jun Ahn, and Suhwan Chang Title of Publication siRNA Nanoparticle Targeting PD-L1 Activates Tumor Immunity and Abrogates Pancreatic Cancer Growth in Humanized Preclinical Model. -
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Mouse Type RID Disease Model Journal PNAS 2022 Vol. 119 No. 30 e2119048119 Author Yeon-Sook Choi, Myung Ji Kim, Eun A. Choi, Sinae Kim, Eun ji Lee, Min Ji Park, Mi-Ju Kim, Yeon Wook Kim, Hee-Sung Ahn , Jae Yun Jung, Gayoung Jang, Yongsub Kim , Hyori Kim , Kyunggon Kim, Jin Young Kim, Seung-Mo Hong, Song Cheol Kim, and Suhwan Chang Title of Publication Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis. -
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Mouse Type SID Disease Model Metastatic gastric cancer Journal Nature Communications (2022) 13:6274 Author Jihee Lee, Kyoungwha Pang, Junil Kim, Eunji Hong, Jeeyun Lee, Hee Jin Cho, Jinah Park, Minjung Son, Sihyun Park,, Minjung Lee, AkiraOoshima, Kyung-Soon Park, Han-Kwang Yang, Kyung-Min Yang& Seong-Jin Kim Title of Publication ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer. -
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Mouse Type SID Disease Model Xeno + NK cell therapy Journal Journal of Experimental & Clinical Cancer Research (2021) 40:333. https://doi.org/10.1186/s13046-021-02089-0 Author Daun Jung, Young Seok Baek, In Jee Lee, Ki Yeon Kim, Heejoo Jang, Sohyun Hwang, Jieun Jung, Yong-wha Moon, Kyung-Soon Park, Yong-Soo Choi and Hee Jung An Title of Publication Ex vivo expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions. -
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Mouse Type SID Disease Model Journal J Immunother Cancer 2022;10:e004964. doi:10.1136/jitc-2022-004964 Author Choi SH, Kim HJ, Park JD, Ko ES, Lee MW, Lee DK, Choi JH, Jang HJ, Kim Issac, Jung HY, Park KH, Park KS Title of Publication Chemical priming of natural killer cells with branched polyethylenimine for cancer immunotherapy. -
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Mouse Type RID Disease Model Cervical cancer Journal Cell Death Dis. 2022 Feb 22;13(2):169. doi: 10.1038/s41419-022-04619-w. Author Pang K, Lee J, Kim J, Park J, Park Y, Hong E, An H, Ooshima A, Son M, Park KS, Cho JH, Lee C, Song YS, Yang KM, Kim SJ Title of Publication Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells. -
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Mouse Type SID Disease Model Bladder orthotopic Journal Experimental & Molecular Medicine; https://doi.org/10.1038/s12276-022-00786-0 Author Jinbeom Heo, Jinyoung Lee, Yun Ji Nam, YongHwan Kim, HongDuck Yun, Seungun Lee, Hyein Ju, Chae-Min Ryu, Seon Min Jeong, Jinwon Lee, Jisun Lim, Yong Mee Cho, Eui Man Jeong, Bumsik Hong, Jaekyoung Son and Dong-Myung Shin Title of Publication The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer. -
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Mouse Type RID Disease Model PDX organoid PDOX Journal Oncol. 2021 Jul 13;2021:9994535. doi: 10.1155/2021/9994535. eCollection 2021. Author Kwon J, Oh S, Park M, Kong JS, Lee S, Lee H, Kim Y, Kang KT, Shin US, Jung J.J Title of Publication Advanced Xenograft Model with Cotransplantation of Patient-Derived Organoids and Endothelial Colony-Forming Cells for Precision Medicine. -
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Mouse Type RID Disease Model Metastatic liver cancer Journal Nutrients. 2021 Dec 28;14(1):134. doi: 10.3390/nu14010134. Author Kwon HJ, Lee S, Lee HH, Cho H, Jung J Title of Publication Korean Red Ginseng Enhances Immunotherapeutic Effects of NK Cells via Eosinophils in Metastatic Liver Cancer Model. -
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Mouse Type SID Disease Model GVHD Treg Journal Adv. Sci. 2021, 2004973 Author Gil-Ran Kim, Won-Ju Kim, Sangho Lim, Hong-Gyun Lee, Ja-Hyun Koo, Kyung-Ho Nam, Sung-Min Kim, Sung-Dong Park, and Je-Min Choi Title of Publication In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse. -
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Mouse Type RID Disease Model Cervical cancer (caski) xeno Journal Cancer Res June 15 2020, 80 (12) 2537-2549 Author Yuna Park, Kyoungwha Pang, Jinah Park, Eunji Hong, Jihee Lee, Akira Ooshima, Hae-Suk Kim, Jae Hyun Cho, Youngjin Han, Cheol Lee, Yong Sang Song, Kyung-Soon Park, Kyung-Min Yang and Seong-Jin Kim Title of Publication Destablilization of TRAF6 by DRAK1 Suppresses Tumor Growth and Metastasis in Cervical Cancer Cells. -
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Mouse Type RID Disease Model Liver regeneration (MSC) Journal Cells 2020 Jun 2;9(6):E1521 Author Jooyoung Lee, Jiwan Choi , Seoon Kang, Jiye Kim, Ryunjin Lee, Seongjun So, Young-In Yoon, Varvara A. Kirchner, Gi-Won Song, Shin Hwang , Sung-Gyu Lee, Eunju Kang and Eunyoung Tak Title of Publication Hepatogenic Potential and Liver Regeneration Effect of Human Liver-derived Mesenchymal-like Stem Cells. -
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Mouse Type SID Disease Model PBMC-GVHD Journal Sci Adv. 2020 Apr; 6(16): eaba1334 Author Jisun Lim, Jinbeom Heo, Hyein Ju, Ji-Woong Shin, YongHwan Kim, Seungun Lee, Hwan Yeul Yu, Chae-Min Ryu, HongDuck Yun, Sujin Song, Ki-Sung Hong, Hyung-Min Chung, Hwa-Ryeon Kim, Jae-Seok Roe, Kihang Choi, In-Gyu Kim, Eui Man Jeong, and Dong-Myung Shin Title of Publication Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway. -
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Mouse Type SID Disease Model Bladder orthotopic Journal EMBO Mol Med 2020 Jan 9;12(1):e10880 Author Jinbeom Heo, Byeong-Joo Noh, Seungun Lee, Hye-Yeon Lee, YongHwan Kim, Jisun Lim, Hyein Ju, Hwan Yeul Yu, Chae-Min Ryu, Peter CW Lee, Hwangkyo Jeong, Yumi Oh, Kyunggon Kim, Sang-Yeob Kim, Jaekyoung Son, Bumsik Hong, Jong Soo Kim, Yong Mee Cho, & Dong-Myung Shin Title of Publication Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis. -
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Mouse Type RID Disease Model Breast cancer Lung metastasis Journal Nature Communications 2019 Dec 20;10(1):5805 Author Kyoungwha Pang, Jinah Park, Sung Gwe Ahn, Jihee Lee, Yuna Park, Akira Ooshima, Seiya Mizuno, Satoshi Yamashita, Kyung-Soon Park, So-Young Lee, Joon Jeong, Toshikazu Ushijima, Kyung-Min Yang & Seong-Jin Kim. Title of Publication RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple negative breast cancers.