Products
Humanized Mouse model
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hHSC(CD34+)engrafted SID mouse
hHSC(CD34+)engrafted SID mouse
This model involves the transplantation of human hematopoietic stem cells (CD34⁺) to enable long-term reconstitution of major immune cells, including T cells, B cells, and NK cells. It is suitable for long-term preclinical studies of immuno-oncology therapies, vaccines, and infectious diseases.
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hPBMC engrafted SID mouse
hPBMC engrafted SID mouse
This model involves the transplantation of human peripheral blood mononuclear cells (PBMCs) to induce immune responses in a short period of time. It is relatively simple and efficient to establish, making it suitable for short-term drug response evaluation, immune activation testing, and cytotoxicity assays. However, long-term observation is limited by the risk of graft-versus-host disease (GvHD).
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Humanized PDX(Patient Derived Xenograft) mouse model
Humanized PDX(Patient Derived Xenograft) mouse model
By engrafting patient-derived tumor tissues (PDX) into humanized mice, this model enables the recreation of interactions between human tumors and the immune system, making it highly useful for preclinical efficacy evaluation of immuno-oncology therapies. It is used for precise efficacy assessment of immunotherapeutics and research on personalized treatment strategies.